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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DRD3 All Species: 6.67
Human Site: Y256 Identified Species: 14.67
UniProt: P35462 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35462 NP_000787.2 400 44225 Y256 H L E L K R Y Y S I C Q D T A
Chimpanzee Pan troglodytes Q5IS72 400 44218 Y256 H L E L K R Y Y S I C Q D T A
Rhesus Macaque Macaca mulatta XP_001085336 414 47327 P261 M L S S T S P P E R T R Y S P
Dog Lupus familis XP_545106 447 49572 R256 P I R Q F S I R D R F P S D A
Cat Felis silvestris
Mouse Mus musculus P30728 446 49651 R256 P I R Q F S I R A R F L S D A
Rat Rattus norvegicus P19020 446 49497 R256 P I R Q F S I R A R F L S D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234083 479 52737 Q260 Q Y Q Y N T G Q S S C R R V S
Frog Xenopus laevis P24628 442 49720 F254 F V K S N G S F P A D K K K V
Zebra Danio Brachydanio rerio Q90WY6 432 49119 S262 R E N G H C S S S P G E R K P
Tiger Blowfish Takifugu rubipres P53453 463 52101 T258 P E D V R L C T M I V K S N G
Fruit Fly Dros. melanogaster NP_001014760 461 51513 R302 E T A L D S S R H A S R I L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 54.8 83.6 N.A. 81.8 80.4 N.A. N.A. 56.7 50.9 34.9 49.6 34.9 N.A. N.A. N.A.
Protein Similarity: 100 99.5 65.9 87 N.A. 85.8 85.1 N.A. N.A. 64 64 52.5 62.2 50.5 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 6.6 6.6 N.A. N.A. 13.3 0 6.6 6.6 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 13.3 N.A. 20 20 N.A. N.A. 33.3 26.6 13.3 33.3 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 19 19 0 0 0 0 46 % A
% Cys: 0 0 0 0 0 10 10 0 0 0 28 0 0 0 0 % C
% Asp: 0 0 10 0 10 0 0 0 10 0 10 0 19 28 0 % D
% Glu: 10 19 19 0 0 0 0 0 10 0 0 10 0 0 0 % E
% Phe: 10 0 0 0 28 0 0 10 0 0 28 0 0 0 0 % F
% Gly: 0 0 0 10 0 10 10 0 0 0 10 0 0 0 10 % G
% His: 19 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 28 0 0 0 0 28 0 0 28 0 0 10 0 0 % I
% Lys: 0 0 10 0 19 0 0 0 0 0 0 19 10 19 0 % K
% Leu: 0 28 0 28 0 10 0 0 0 0 0 19 0 10 0 % L
% Met: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 19 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 37 0 0 0 0 0 10 10 10 10 0 10 0 0 28 % P
% Gln: 10 0 10 28 0 0 0 10 0 0 0 19 0 0 0 % Q
% Arg: 10 0 28 0 10 19 0 37 0 37 0 28 19 0 0 % R
% Ser: 0 0 10 19 0 46 28 10 37 10 10 0 37 10 10 % S
% Thr: 0 10 0 0 10 10 0 10 0 0 10 0 0 19 0 % T
% Val: 0 10 0 10 0 0 0 0 0 0 10 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 10 0 0 19 19 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _